I et interview med GameInformer fortæller Neil Druckmann og Bruce Straley, at det dog ikke altid er lige nemt at få performance og grafik til at harmonere med hinanden. Naughty Dog kæmper blandt andet med frameraten og det er ikke nogen nem opgave at få spillet til at køre stabilt med 60 billeder i sekundet:
Really fucking hard. I mean, but thats true for any game. It was really hard on The Last of Us Remastered, and thats a game we have finished, and we knew exactly what the end result needs to look like. Here were trying to push the boundaries of what this game can look and do real-time cutscenes, and trying to do sixty (billeder i sekundet), is really hard.
The objective for us is just to make the best experience. Right now were trying to push the look, and then well see where were at, and well re-assess. Were constantly making choices throughout production of whats going to make the game feel best, and look its best.
Foruden framerates blev der også diskuteret photo-mode til spillet, ligesom at hverken Druckmann eller Straley ville udelukke, at Uncharted serien ville udkomme i en såkaldt remaster-udgave til PlayStation 4.